Mastitis: Impact of Dry Period, Pathogens, and Immune Responses on Etiopathogenesis of Disease and its Association with Periparturient Diseases

Mastitis is an inflammation of the mammary gland initiated by pathogenic bacteria. In fact, mastitis second most important reason for culling cows from dairy herds, after infertility. this review we focus on various forms mastitis, including subclinical and clinical mastitis. We also stress importance dry-off period as time when bacteria might start their insult to gland. An part negative effects milk production composition, well economic consequences farms. The two groups that are involved in infection udder, Gram-negative Gram-positive bacteria, discussed. Although all have both innate adaptive immunity against pathogens, some more susceptible disease than others. That why summarize components so reader understands specific immune responses udder One sections interrelationship with other diseases, especially retained placenta, metritis endometritis, ketosis, laminitis. Is cause or consequence disease? Finally, concludes treatment preventive approaches